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Dibutylone is a cathinone stimulant that goes by the alternate names “bk-DMBDB”, “booty” and “beauty”. Still other names for dibutylone include β-Keto-dimethylbenzodioxolylbutanamine, bk-DMBDB and 1-(1,3-Benzodioxol-5-yl)-2-(dimethylamino)butan-1-one.
It goes under the formal and systematic IUPAC name 1-(Benzo[d][1,3]dioxol-5-yl)-2-(dimethylamino)butan-1-one. It has a molar mass of 235.28 grams and empirical chemical formula C13H17NO3.
It is speculated that dibutylone acts as a prodrug for butylone. It is also structurally related to methylone a popular cathinone.
Cathinones act to increase the concentration of neurotransmitters serotonin, dopamine and noradrenaline by inhibiting monoamine transporters and mild stimulation of monoamine release. Increased monoamine concentration at the synapse produces feelings of stimulation, well being and euphoria. Dopamine is a monoamine neurotransmitter which plays a role in reward pathways.
External reward stimulus such as food and sex cause a release of dopamine in the brain. These feelings are intrinsically positive. Thus increased action of dopamine in the brain induced by drugs such as cathinones produces feelings of well being. Serotonin is a major neurotransmitter which is implicated in the “loved up” feeling produced by the street drug MDMA or ecstasy. Cathinones which inhibit serotonin reuptake and induce serotonin release will replicate this entactogenic feeling.
The substituted cathinones are beta keto analogues of amphetamine. In the last decade they have been described as a new emerging class of abused stimulants. Cathinone was first identified in 1975 as the primary psychoactive component in the herbal stimulant Khat, a leaf based drug made from the plant Catha edulis which grows wild in the horn of Africa. It has a long history of use over many hundreds of years in the Middle East as a stimulant.
In recent times there has been an eruption of novel cathinone derivatives in the designer drug market. However it is interesting to note that substituted cathinones have an earlier history of use. Methcathinone was significant drug of abuse in the Soviet Union in the 1980s and went by the name ephedrone.
The cathinones all consist of a phenylamine backbone with a ketone at the beta carbon and various alkyl substituents at the alpha carbon. Substitutions can be made to the aryl ring and to the amine.
Dibutylone specifically has a dioxyl substituent on the aryl ring reminiscent of MDMA. The tertiary amine has two methyl substituents and the alpha carbon has an ethyl substituent.
Based on its structure it would be expected to have effects similar to the cathinone stimulant butylone however this is conjecture.
Dibutylone has a very short period of human use. The long term health implications of use are unknown. There are no scientific studies in to the pharmacological effects of dibutylone or its potential toxicology.
Dibutylone is not for human or animal consumption.
Tentative and unverifiable online reports claim that the compound has a mild stimulatory effect.
It is worth noting that the cathinone series has potential for abuse. Many of the compounds cause users to compulsively re-dose. Caution should be exercised with respect to dose. It should not be mixed with alcohol or other substances.